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Recycling of oxidized GSH (GSSG) back to its reduced form is facilitated by glutathione reductase (GSR) using NADPH from the pentose phosphate pathway

Science 338 , 818822 (2012)

This susceptibility stems from reduced basal GSH levels caused by impaired plasma membrane expression of SLC7A11

A pivotal 2007 study published in the Journal of Physiology and Pharmacology examined rats with experimentally induced esophagitis and sphincter failure

-Amyloid accumulation in the human brain after one night of sleep deprivation